Not Lilly. Not Johnson & Johnson. This Stock Will Be the Biggest Healthcare Winner of 2026
Healthcare stocks have rebounded this year. Many leaders in the sector have helped drive that performance. Eli Lilly (NYSE: LLY), the largest healthcare stock by market cap, has gained 16%, while Johnson & Johnson (NYSE: JNJ), another major healthcare player, has climbed 22%. However, among large-cap healthcare stocks, none has performed better than Moderna (NASDAQ: MRNA). The vaccine maker has soared over 600%, as of writing. Moderna is on track to be the biggest healthcare winner among large-cap stocks in 2026. But does that make the stock a buy?
Moderna rose to prominence after developing an effective coronavirus vaccine in record time during the early days of the pandemic. The biotech was well rewarded for its efforts. But demand for COVID-19 vaccines has declined in recent years. And even though Moderna had made some clinical and regulatory progress outside of that area — it notably earned approval for a respiratory syncytial virus — that has not allowed the company to maintain consistent revenue and earnings growth. That may be about to change.
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